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SYN2219781
SynDRA canonical compound SYN2219781 — structure-anchored drug synonym record
| Clinical phase | Phase 1 |
|---|
| Primary target(s) | CDK4 | CDK6 | FLT3 |
|---|
| Mechanism of action | CDK inhibitor | FLT3 inhibitor |
|---|
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- CCNB1
- CCND1
- CDK1
- KSYK
- NSD2
- SYK
- TP53
Cross-references
Synonyms
- AMG 925
- FLX925
- FLX925 (AMG-925)
- RB6Y814V4I
- MFCD28155269
- UNII-RB6Y814V4I
- AMG925
- FLX 925
- orb1300495
- SCHEMBL12540289
- SCHEMBL12540291
- SCHEMBL29360158
- SCHEMBL29903226
- SCHEMBL30471366
- CHEBI:145537
- BDBM112464
- GLXC-90180
- AMG 925?
- EX-A9264
- AMG-925 (FLX925)
- BDBM50601439
- NSC781514
- s7533
- AKOS025404929
- EBC-519716
- NSC-781514
- SB18929
- NCGC00384220-04
- AC-33001
- AS-17036
- BP-42845
- DA-60987
- FA137647
- HY-15889
- SY387863
- T6756
- US8623885, 5
- A488244
- BRD-K97452254-001-01-3
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