AMG-PERK-44

SynDRA canonical compound SYN1501485 — structure-anchored drug synonym record

Clinical phase	Preclinical
Primary target(s)	EIF2AK4
Mechanism of action	PERK inhibitor

All known targets

EIF2AK4

Mechanisms of action (all sources)

EIF2AK3 INHIBITOR

Bioactivity evidence (ChEMBL activities table — not curator-asserted)

EIF2AK3
BRAF
EIF2AK4

Cross-references

PubChem CID: 86583045
ChEMBL: CHEMBL3407862
PDB: 3Z5

Synonyms

CHEMBL3407862
SCHEMBL23943615
SCHEMBL30100847
BDBM50072036
NCGC00480730-01
NCGC00480730-02
3Z5
4-[2-amino-4-methyl-3-(2-methylquinolin-6-yl)benzoyl]-1-methyl-2,5-diphenyl-1,2-dihydro-3H-pyrazol-3-one

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