← SynDRA

CHEMBL2441340

SynDRA canonical compound SYN1360062 — structure-anchored drug synonym record

All known targets

• EIF2AK3

Mechanisms of action (all sources)

• EIF2AK3 INHIBITOR

Bioactivity evidence (ChEMBL activities table — not curator-asserted)

• EIF2AK3
• RIPK1

Cross-references

• PubChem CID: 53469059
• ChEMBL: CHEMBL2441340
• ChEBI: 139047

Synonyms

• GSK2656157
• GSK 2656157
• 1-(5-(4-amino-7-methyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)-4-fluoroindolin-1-yl)-2-(6-methylpyridin-2-yl)ethanone
• SCHEMBL870782
• PERK inhibitor GSK2656157
• 1-[5-(4-amino-7-methylpyrrolo[2,3-d]pyrimidin-5-yl)-4-fluoro-2,3-dihydroindol-1-yl]-2-(6-methylpyridin-2-yl)ethanone
• AGN-PC-09SWN4
• GTPL9544
• EX-A439
• CHEBI:139047
• DTXSID101103941
• HMS3652P16
• HMS3747M09
• HMS3868L13
• BCP09007
• BDBM50442166
• MFCD27997885
• s7033
• ZINC96170461
• AKOS025404913
• CCG-268839
• compound 6 [PMID: 24900593]
• CS-3262
• SB19409
• NCGC00386314-01
• NCGC00386314-03
• 1-(5-(4-amino-7-methyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)-4-fluoroindolin-1-yl)-2-(6-methylpyridin-2-yl)ethan-1-one
• AC-32973
• AS-35165
• DA-31727
• HY-13820
• FT-0734440
• SW222243-1
• J-006434
• 1-[5-(4-Amino-7-methyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)-4-fluoro-2,3-dihydro-1H-indol-1-yl]-2-(6-methyl-2-pyridinyl)-ethanone
• 1-[5-(4-Amino-7-methyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)-4-fluoro-2,3-dihydro-1H-indol-1-yl]-2-(6-methyl-2-pyridinyl)ethanone
• 5-{4-fluoro-1-[(6-methyl-2-pyridinyl)acetyl]-2,3-dihydro-1H-indol-5-yl}-7-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine
• 5-{4-fluoro-1[(6-methyl-2-pyridinyl)acetyl]-2,3-dihydro-1H-indol-5-yl}-7-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine
• Gsk2656157