← SynDRA
CGP-37157
SynDRA canonical compound SYN0816930 — structure-anchored drug synonym record
| Clinical phase | Preclinical |
|---|
| Primary target(s) | SLC8A1 |
|---|
| Mechanism of action | Mitochondrial Na+/Ca2+ exchanger antagonist |
|---|
All known targets
Mechanisms of action (all sources)
- L-type calcium channel blocker
- Sodium/calcium exchange inhibitor
- Mitochondrial Na+/Ca2+ exchanger antagonist
- SLC8B1 INHIBITOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ATAD5
- ATXN2
- GLP1R
- GNAS
- NPSR1
- SMAD3
- TARDBP
- TDP1
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
Cross-references
Synonyms
- Tocris-1114
- NCGC00025008-01
- PD132790
- Bio2_000756
- HMS3676I15
- SR-01000597388-1
- HMS3412I15
- HMS3267K16
- GLXC-15871
- BRD-A35623999-001-02-4
- HMS3867M03
- KBioGR_000276
- BRD-A35623999-001-04-0
- HY-15754
- Bio1_000408
- HMS1361N18
- BDBM50139422
- NCGC00025008-03
- HMS1989N18
- BSPBio_001556
- SR-01000597388
- Cgp 37157
- DB-055958
- Bio1_001386
- GTPL11611
- SCHEMBL31071906
- KBioSS_000276
- HSCI1_000330
- BRD-A35623999-001-03-2
- NCGC00025008-02
- T14941
- CGP37157
- KBio3_000552
- RefChem:124784
- KBio2_005412
- Bio1_000897
- HMS1791N18
- CHEBI:91650
- 7-chloro-5-(2-chlorophenyl)-1,5-dihydro-4,1-benzothiazepin-2-one
Look up CGP-37157 in the interactive SynDRA portal →