Tocris-2007

SynDRA canonical compound SYN0804469 — structure-anchored drug synonym record

Primary target(s)	PGR
Mechanism of action	Glucocorticoid receptor agonist

All known targets

NR3C1
PGR

Mechanisms of action (all sources)

NR3C1 AGONIST

Bioactivity evidence (ChEMBL activities table — not curator-asserted)

ATAD5
ATXN2
GLP1R
GMNN
HCRTR1
HCRTR2
KDM4A
L3MBTL1
NFE2L2
PIN1
PLK1
SMAD3
TDP1
USP1

Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)

MDM2
MDM4
OX2R

Cross-references

PubChem CID: 6604930
ChEMBL: CHEMBL1433930
ChEBI: CHEBI:91778
LINCS BRD: BRD-A59943784

Synonyms

NCGC00025343-01
fluticasone
HMS3268F07
CHEBI:91778
BRD-A59943784-001-01-8
6,9-difluoro-11-hydroxy-17-(3-hydroxy-2-oxopropyl)-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthrene-17-carbothioic acid S-(fluoromethyl) ester

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