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Tyrphostin B56
SynDRA canonical compound SYN0156696 — structure-anchored drug synonym record
| Clinical phase | Preclinical |
|---|
| Mechanism of action | tyrosine kinase inhibitor |
|---|
Mechanisms of action (all sources)
- tyrosine kinase inhibitor
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- EGFR
- ALDH1A1
- PMP22
- KDM4A
- KDM4E
- MAPK1
- MAPT
- MPHOSPH8
- MTOR
- NFKB1
- PIN1
- PKM
- POLH
- JAK2
- POLI
- POLK
- RECQL
- RGS4
- SMN1
- TARDBP
- TDP1
- THPO
- TP53
- TSHR
- KCNH2
- HSPA5
- ALOX12
- CYP2C9
- ALOX15
- ARSA
- ATAD5
- ATXN2
- BAZ2B
- BLM
- CBX1
- CYP1A2
- CYP2C19
- CYP2D6
- HSD17B10
- CYP3A4
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- ALR
- HS90B
- PHGDH
- PAFA2
- PAFA
- PA1B2
- NTM1A
- NNMT
- MCL1
- LOX15
- HS90A
- B2CL1
- HNMT
- GNMT
- GLSK
- GAMT
- FUMH
- CP3A4
- CP1A2
- COMT
- PNMT
Cross-references
Synonyms
- AG 556
- Tyrphostin AG556
- ag556
- alpha-Cyano-(3,4-dihydroxy)-N-(4-phenylbutyl)cinnamide
- N-(4-Phenylbutyl)-3,4-dihydroxybenzylidene cyanoacetamide
- RefChem:915236
- (E)-AG 556
- 2-Cyano-3-(3,4-dihydroxyphenyl)-N-(4-phenylbutyl)acrylamide
- SR-01000597669
- Tocris-0616
- Tyrphostin deriv. 56
- BDBM4308
- orb1306176
- SCHEMBL2533402
- HMS3414I03
- HMS3678I03
- HSCI1_000058
- MFCD00209860
- AKOS024458582
- NCGC00024686-01
- TS-08209
- F81725
- T21853
- SR-01000597669-1
- SR-01000597669-2
- BRD-K81048131-001-01-6
- BRD-K81048131-001-02-4
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