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KN-62
SynDRA canonical compound SYN0114851 — structure-anchored drug synonym record
| Primary target(s) | CAMK2A |
|---|
| Mechanism of action | Calcium/calmodulin dependent protein kinase inhibitor |
|---|
All known targets
- P2RX7
- AKT1
- CAMK2A
- CHEK1
- LCK
- MAPK1
- MAPK11
- MAPK12
- MAPK14
- MAPK8
- PRKCA
- ROCK1
Mechanisms of action (all sources)
- Purinergic receptor antagonist
- Calcium/calmodulin dependent protein kinase inhibitor
- P2RX7 NEGATIVE ALLOSTERIC MODULATOR
- RPS6KB1 INHIBITOR
- CHEK1 INHIBITOR
- ROCK1 INHIBITOR
- MAPK12 INHIBITOR
- MAPK1 INHIBITOR
- SGK1 INHIBITOR
- PRKCA INHIBITOR
- MAPK11 INHIBITOR
- P2RX7 INHIBITOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
Cross-references
Synonyms
- KN 62
- RefChem:1069640
- KN62
- MFCD00083180
- SMR000058456
- UNII-63HM46XPOW
- KN62 (S isomer)
- CBiol_002006
- Lopac0_000620
- MLS000028868
- MLS006011204
- SCHEMBL379481
- GTPL4235
- SCHEMBL29375343
- SCHEMBL30076662
- SCHEMBL31060656
- KN-62, >=95%, powder
- CHEBI:131159
- Bio1_000292
- Bio1_000781
- Bio1_001270
- GLXC-04616
- HMS2235I16
- HMS3648M08
- HMS3886F15
- EX-A2396
- BDBM50087267
- HB0359
- KN-62?
- s7422
- AKOS005145990
- CCG-270407
- CS-0516
- EBC-218043
- FB24811
- SDCCGSBI-0086769.P003
- SDCCGSBI-0654267.P001
- KN62; KN-62; KN 62
- NCGC00162398-01
- NCGC00162398-02
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