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RS-79948
SynDRA canonical compound SYN0087260 — structure-anchored drug synonym record
| Clinical phase | Preclinical |
|---|
| Primary target(s) | ADRA2A |
|---|
| Mechanism of action | Adrenergic receptor antagonist |
|---|
All known targets
Mechanisms of action (all sources)
- Adrenergic receptor antagonist
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ALOX15B
- GMNN
- TSHR
- TP53
- TDP1
- SMAD3
- PTH1R
- KDM4A
- IDH1
- HDAC6
- GLP1R
- ATXN2
- GBA1
- EHMT2
- CYP3A4
- CYP2D6
- CYP2C9
- CYP2C19
- CYP1A2
- BAZ2B
- USP1
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- APAF
- CP1A2
- CP2D6
- DRD1
- DRD3
- IFNG
- MAPT
- NSD2
- OXYR
Cross-references
Synonyms
- RS 79948
- RS79948
- RefChem:930937
- SCHEMBL12648479
- SCHEMBL29432821
- CHEBI:93509
- GTPL13128
- BRD-K86600316-003-01-2
- BRD-K86600316-003-02-0
- E3F
- (8aR,12aS,13aS)-12-ethylsulfonyl-3-methoxy-5,6,8,8a,9,10,11,12a,13,13a-decahydroisoquinolino[2,1-g][1,6]naphthyridine
- NCGC00024918-01
- NCGC00024918-02
- Tocris-0987
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