sertraline

SynDRA canonical compound SYN0087240 — structure-anchored drug synonym record

Primary target(s)	SLC6A4
Mechanism of action	Serotonin receptor antagonist

All known targets

SLC6A4

Mechanisms of action (all sources)

Serotonin receptor antagonist

Bioactivity evidence (ChEMBL activities table — not curator-asserted)

GLP1R
GMNN
HIF1A
IDH1
LMNA
SAMHD1
SMN1
TDP1

Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)

ITA4
TLR3

Cross-references

PubChem CID: 6093397
ChEMBL: CHEMBL5221702
ChEBI: 94663
LINCS BRD: BRD-K57174586

Synonyms

CP-52002
(1S,4R)-Sertraline
Sertraline, (1S,4R)-
5F33YNB65X
SCHEMBL3841967
BDBM82216
CHEBI:94663
VGKDLMBJGBXTGI-PXAZEXFGSA-N
CP52002
QTL1_000074
BRD-K57174586-001-01-0
(1S,4R)-4-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrahydronaphthalen-1-amine
AKOS030242813
Sertraline Impurity 15
SCHEMBL7757884
SCHEMBL29895228
(1S,4R) Sertraline Hydrochloride

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