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SB-200646
SynDRA canonical compound SYN0087237 — structure-anchored drug synonym record
| Clinical phase | Preclinical |
|---|
| Primary target(s) | HTR2C |
|---|
| Mechanism of action | Serotonin receptor antagonist |
|---|
All known targets
Mechanisms of action (all sources)
- Serotonin receptor antagonist
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- HTR1B
- ADRA1B
- HTR1D
- HTR1E
- HTR1F
- HTR2A
- HTR2B
- HTR2C
- HTR1A
- HTR4
- HTR5A
- HTR6
- DRD3
- DRD2
- MBD4
- MPG
- HTR3A
- KCNH2
- NEIL1
- ADGRF1
- NPSR1
- OGG1
- TSPO
- TMEM97
- TDG
- SMUG1
- SMN1
- SLC6A4
- SLC6A3
- SLC6A2
- SIGMAR1
- SAMHD1
- S1PR1
- RGS4
- OPRM1
- OPRK1
- OPRD1
- NEIL2
- HRH3
- HRH4
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
Cross-references
Synonyms
- N-(1-Methyl-5-indolyl)-N'-(3-pyridyl)urea
- Mip-urea
- N-(1-Methyl-1H-indol-5-yl)-N'-3-pyridinylurea
- SKB-200646A
- RefChem:926586
- DTXCID9085041
- SB 200646A
- SB 200646
- 1-(1-Methyl-1H-indol-5-yl)-3-(pyridin-3-yl)urea
- 1-(1-methylindol-5-yl)-3-pyridin-3-ylurea
- Tocris-1371
- RT8F72CL8L
- 1-(1-methylindol-5-yl)-3-(3-pyridyl)urea
- SB200646
- SB-200646 hydrochloride
- SB 200646 HCl
- MFCD06248908
- UNII-RT8F72CL8L
- SCHEMBL173735
- CHEBI:8976
- orb1299004
- SCHEMBL29391435
- SCHEMBL29729330
- BDBM82272
- SB200646a
- PDSP1_001636
- PDSP2_001620
- s2649
- AKOS027422836
- HY-103129A
- SB52247
- NCGC00025128-01
- NCGC00025128-02
- DA-57694
- TS-09792
- CS-0119679
- T8357
- F77821
- N-(1-methyl-5-indolyl)-N'-(3-pyridyl) urea
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