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JNJ-16259685
SynDRA canonical compound SYN0087203 — structure-anchored drug synonym record
| Clinical phase | Preclinical |
|---|
| Primary target(s) | GRM1 |
|---|
| Mechanism of action | Glutamate receptor antagonist |
|---|
All known targets
Mechanisms of action (all sources)
- Glutamate receptor antagonist
- GRM1 NEGATIVE ALLOSTERIC MODULATOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ALB
- ALDH1A1
- CYP1A2
- CYP2C19
- CYP2C9
- CYP2D6
- CYP3A4
- HDAC6
- RGS4
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
Cross-references
Synonyms
- Jnj16259685
- JNJ 16259685
- RefChem:150558
- DTXCID90412911
- trans-JNJ 16259685
- JNJ16259865
- HMS3268N12
- MFCD08690525
- MLS006010862
- GTPL1385
- orb1301732
- SCHEMBL13597853
- SCHEMBL15215814
- SCHEMBL16426894
- SCHEMBL29678295
- SCHEMBL30853215
- CHEBI:93132
- BDBM438374
- GLXC-02593
- HMS3413G10
- HMS3677G10
- EX-A2496
- JRA34529
- BDBM50163592
- HB0348
- AKOS024457055
- AKOS030255489
- CS-5874
- NCGC00092375-01
- NCGC00092375-02
- NCGC00092375-03
- DA-54540
- MS-24858
- SMR004701790
- HY-100407
- T5512
- F85437
- US10618900, No. JNJ16259685
- BRD-K25596805-001-01-8
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