fluphenazine

SynDRA canonical compound SYN0087163 — structure-anchored drug synonym record

Primary target(s)	DRD2
Mechanism of action	Dopamine receptor antagonist

All known targets

DRD1
DRD2

Mechanisms of action (all sources)

Dopamine receptor antagonist

Bioactivity evidence (ChEMBL activities table — not curator-asserted)

DRD2
DRD4
CYP1A2
CYP2C19
CYP2C9
CYP2D6
CYP3A4
HDAC6
MAPT
RGS4
SMN1
TDP1

Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)

5HT2A
ACM1
ADRB2
ANDR
CP1A2
CP2CJ
CP2D6
ESRRA
GLI3
HTR3A
HTR3B
HTR3C
HTR3D
HTR3E
KCNH2
TSHR

Cross-references

PubChem CID: 134141
ChEMBL: CHEMBL1623055
ChEBI: 92944
LINCS BRD: BRD-K53987533

Synonyms

fluphenazine-N-mustard
Fluphenazine-N-2-chloroethane
N-Chloroethyl-fluphenazine
Skf 7172-A2
SKF7171A
SKF 7171A
SKF7172-A2
RefChem:141018
SK&F 7172-A2
SCHEMBL8218991
CHEBI:92944
HSCI1_000317
STK109765
AKOS003646923
NCGC00246297-01
PD044969
AO-365/15161001
BRD-K53987533-003-01-9
10-[3-[4-(2-chloroethyl)-1-piperazinyl]propyl]-2-(trifluoromethyl)phenothiazine
MLS000552586
NSC62325
SMR000146101
MLS001306391
DAA89278
NSC-62325

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