dolutegravir

SynDRA canonical compound SYN0086929 — structure-anchored drug synonym record

Primary target(s)	UGT1A1
Mechanism of action	HIV integrase inhibitor

All known targets

CYP3A4
CYP3A5
CYP3A7
POU2F2
UGT1A1

Mechanisms of action (all sources)

HIV integrase INHIBITOR

Bioactivity evidence (ChEMBL activities table — not curator-asserted)

L3MBTL1
OPRD1
OPRM1
POLI
TDP1

Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)

CP2C9
CP3A7
NPY1R
OPRD
OPRM

Cross-references

PubChem CID: 117853645
ChEMBL: CHEMBL4303416
LINCS BRD: BRD-K36386086

Synonyms

FGD6SPP2VH
dolutegravir S,S-
RefChem:920609
Dolutegravir S,S-isomer
UNII-FGD6SPP2VH
Dolutegravir Impurity 4
Dolutegravir Impurity 43
SCHEMBL16440366
PD062931
SW219312-1
BRD-K36386086-001-01-1

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