fludarabine

SynDRA canonical compound SYN0086924 — structure-anchored drug synonym record

Primary target(s)	RRM1
Mechanism of action	DNA synthesis inhibitor

All known targets

RRM1

Mechanisms of action (all sources)

DNA synthesis inhibitor

Bioactivity evidence (ChEMBL activities table — not curator-asserted)

ADORA3
ATXN2
GLP1R
GMNN
IDH1
NFE2L2
SMAD3
TDP1

Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)

CFTR
MITF
RGS4
PRIO
PAX8
OPRM
NR5A2
NCOA3
NCOA2
NCOA1
MDR1
COT2
MDM4
MDM2
IL1B
IDHC
HIF1A
GEMI
EPAS1
CSTA
TR10B

Cross-references

PubChem CID: 57007282
ChEBI: 94359
LINCS BRD: BRD-A31374339

Synonyms

SCHEMBL3655059
CHEBI:94359
BRD-A31374339-001-01-9
(2R,5R)-2-(6-amino-2-fluoro-9-purinyl)-5-(hydroxymethyl)oxolane-3,4-diol

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