JWE-035

SynDRA canonical compound SYN0086900 — structure-anchored drug synonym record

Primary target(s)	AURKA
Mechanism of action	Aurora kinase inhibitor

All known targets

AURKA

Mechanisms of action (all sources)

aurora kinase inhibitor

Bioactivity evidence (ChEMBL activities table — not curator-asserted)

CYP3A4
CHRM1
CHRM2
CHRM3
HDAC6

Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)

CP2C9
CP3A7
KSYK
NSD2
SYK
TP53

Cross-references

PubChem CID: 57340671
ChEBI: 91374
LINCS BRD: BRD-K83972459

Synonyms

SCHEMBL16980224
BDBM86617
CHEBI:91374
PXGLIUGVLBRUBV-UHFFFAOYSA-N
HMS3295A09
BRD-K83972459-001-01-9
Benzo[e]pyrimido[5,4-b][1,4]diazepin-6(11H)-one, 23
2-[4-[(4-ethyl-1-piperazinyl)methyl]-3-(trifluoromethyl)anilino]-5,11-dimethyl-6-pyrimido[4,5-b][1,4]benzodiazepinone

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