tetrahydrobiopterin

SynDRA canonical compound SYN0086893 — structure-anchored drug synonym record

Primary target(s)	TH
Mechanism of action	Phenylalanine 4-hydroxylase stimulant

All known targets

PAH
TH

Mechanisms of action (all sources)

Nitric oxide stimulant
Nitric oxide synthase stimulant
Phenylalanine 4-hydroxylase stimulant

Bioactivity evidence (ChEMBL activities table — not curator-asserted)

TMEM97
APEX1
CYP1A2
CYP2C19
CYP2C9
CYP2D6
CYP3A4
HDAC6
MAPK1
RGS4
TSHR

Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)

CP2CJ
CP2D6

Cross-references

PubChem CID: 136188272
ChEBI: 94423
LINCS BRD: BRD-A67605442

Synonyms

SCHEMBL31673726
CHEBI:94423
BRD-A67605442-001-01-7
2-amino-6-[(1R)-1,2-dihydroxypropyl]-5,6,7,8-tetrahydro-1H-pteridin-4-one

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