nelfinavir

SynDRA canonical compound SYN0086883 — structure-anchored drug synonym record

Primary target(s)	CYP3A4
Mechanism of action	HIV protease inhibitor

All known targets

CYP1A2
CYP2B6
CYP2C19
CYP2C9
CYP2D6
CYP3A4
CYP3A7

Mechanisms of action (all sources)

protease inhibitor

Bioactivity evidence (ChEMBL activities table — not curator-asserted)

ADRB2
ALOX15
ALOX15B
ALOX5
KDM4E
L3MBTL1
NFE2L2
NPC1
PIN1
PTGS2
RAB9A
RAPGEF3
RAPGEF4
SMAD3

Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)

ABL1
ADCY9
ATXN2
LOX12
PA2G3
RIN1
SIAE

Cross-references

PubChem CID: 73707414
ChEBI: 94678
LINCS BRD: BRD-K60460488

Synonyms

CHEBI:94678
BRD-K60460488-066-01-0
(3S,4aR,8aR)-N-tert-butyl-2-[(2R,3R)-2-hydroxy-3-[(3-hydroxy-2-methylbenzoyl)amino]-4-phenylsulfanylbutyl]-3,4,4a,5,6,7,8,8a-octahydro-1H-isoquinoline-3-carboxamide

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