← SynDRA

FK-888

SynDRA canonical compound SYN0086857 — structure-anchored drug synonym record

All known targets

• TACR1
• TACR2

Mechanisms of action (all sources)

• Tachykinin antagonist
• TACR1 ANTAGONIST
• TACR2 ANTAGONIST

Bioactivity evidence (ChEMBL activities table — not curator-asserted)

• GLP1R
• ADGRF1
• GPR35
• TDG
• SMUG1
• S1PR1
• NTHL1
• NEIL1
• MUTYH
• MPG
• MBD4
• GPR119
• ADRA2A
• FPR2
• FFAR4
• CX3CR1
• C5AR1
• APLNR
• AGTR1
• ADRB2
• UNG

Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)

• CP2D6
• KSYK
• SYK

Cross-references

• PubChem CID: 107967
• ChEMBL: CHEMBL1416993
• ChEBI: 93463
• TTD: D05UKK
• LINCS BRD: BRD-K83508485

Synonyms

• FK 888
• FK888
• DZQ7B7BPD4
• RefChem:140529
• DTXCID0083171
• HMS3269A13
• GTPL2114
• SCHEMBL8079679
• SCHEMBL29407233
• CHEBI:93463
• HMS3413K12
• HMS3677K12
• EX-A14256
• PDSP2_000648
• AKOS024457076
• NCGC00159560-01
• DA-73376
• FH157382
• MS-33244
• HY-105215
• CS-0025377
• H49699
• BRD-K83508485-001-01-9
• BRD-K83508485-001-02-7
• BRD-K83508485-001-03-5
• L-alaninamide
• orb2703452
• L001421
• BDBM50030178