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MG-132
SynDRA canonical compound SYN0086823 — structure-anchored drug synonym record
| Clinical phase | Preclinical |
|---|
| Primary target(s) | PSMB1 |
|---|
| Mechanism of action | Proteasome inhibitor |
|---|
All known targets
Mechanisms of action (all sources)
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ALOX15
- HSPA5
- USP1
- TSHR
- TP53
- TDP1
- MAPT
- KDM4E
- HSD17B10
- APOBEC3G
- HPGD
- CYP3A4
- CYP2D6
- CYP2C9
- CYP2C19
- CYP1A2
- YES1
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- ALOX12
- ATXN2
- CP1A2
- CP2D6
- CP3A4
- GPX4
- HLAB
- IFNB1
- LOX12
- LOX15
- NSD2
- NTM1A
- NTMT1
Cross-references
Synonyms
- Z-Leu-leu-leu-al
- MG132
- Zlllal
- Z-Leu-leu-leucinal
- Z-LLL-CHO
- Zlll-cho
- Lll cpd
- Carbobenzoxy-leucyl-leucyl-leucinal
- Z-LLL
- Benzyloxycarbonyl-leucyl-leucyl-leucinal
- Benzyloxycarbonyl-leu-leu-leu-aldehyde
- Benzyloxycarbonylleucyl-leucyl-leucine aldehyde
- Carbobenzoxyl-leucinyl-leucinyl-leucinal-H
- RF1P63GW3K
- CHEBI:75142
- n-benzyloxycarbonyl-l-leucyl-l-leucyl-l-leucinal
- carbobenzyloxy-leucinyl-leucinyl-leucinal
- RefChem:818803
- Proteasome Inhibitor MG-132
- DTXCID1022639
- Z-Leu-Leu-Leu-H
- C26H41N3O5
- MFCD00674886
- Cbz-Leu-Leu-Leu-H
- Cbz-L-Leu-L-Leu-L-Leu-CHO
- BRD0970
- BRD-0970
- Z-LLL-H
- UNII-RF1P63GW3K
- Carbobenzoxy-L-leucyl-L-leucyl-L-leucinal
- zLLL
- Z-LLLal
- Cbz-Leu-Leu-Leucinal
- Z-L-leu-L-leu-L-leu-H
- BSPBio_001310
- carbobenzoxy-Leu-Leu-leucinal
- KBioGR_000030
- KBioSS_000030
- MLS006011220
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