XMD-885

SynDRA canonical compound SYN0086819 — structure-anchored drug synonym record

Primary target(s)	MAPK7
Mechanism of action	Leucine rich repeat kinase inhibitor

All known targets

LRRK2
MAPK7

Mechanisms of action (all sources)

MEK inhibitor
Leucine rich repeat kinase inhibitor

Bioactivity evidence (ChEMBL activities table — not curator-asserted)

ALDH1A1
ALOX15
TP53
TDP1
SMN1
SMAD3
PIN1
NPSR1
NPC1
MAPT
LMNA
IDH1
HTT
HPGD
HDAC6
GMNN
GLP1R
GBA1
EHMT2
CGA
ATXN2
ATAD5
APOBEC3G
APOBEC3F
APEX1
USP2

Cross-references

PubChem CID: 46844147
ChEMBL: CHEMBL1673039
ChEBI: 91375
PDB: X7Y
LINCS BRD: BRD-K64857848

Synonyms

XMD8-85
SCHEMBL618262
orb1302017
SCHEMBL29360090
SCHEMBL31092834
CHEBI:91375
C25H29N7O2
HMS3295A11
EX-A3073
JZB47976
BDBM50337127
ZB1553
ERK5-IN-1 XMD 8-85
AKOS030526340
CS-4938
EBC-521728
XMD17-109 (ERK5-IN-1)
AC-36310
BS-14786
HY-14403
T5184
D71039
BRD-K64857848-001-01-5
BRD-K64857848-001-06-4
X7Y
2-[2-methoxy-4-(4-methyl-1-piperazinyl)anilino]-5,11-dimethyl-6-pyrimido[4,5-b][1,4]benzodiazepinone

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