EO-1428

SynDRA canonical compound SYN0086783 — structure-anchored drug synonym record

Clinical phase	Preclinical
Primary target(s)	MAPK11
Mechanism of action	P38 MAPK inhibitor

All known targets

MAPK11
MAPK14

Mechanisms of action (all sources)

MAPK14 INHIBITOR

Bioactivity evidence (ChEMBL activities table — not curator-asserted)

ATAD5
ATXN2
CBX1
EHMT2
FEN1
HDAC6
USP1
VDR

Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)

ESRRA
KSYK
SYK

Cross-references

PubChem CID: 9801969
ChEMBL: CHEMBL347496
ChEBI: 91468
LINCS BRD: BRD-K42452249

Synonyms

UNII-MV2RHJ680O
MV2RHJ680O
RefChem:137070
DTXCID10108405
p38 MAPK Inhibitor VIII
HDCLCHNAEZNGNV-UHFFFAOYSA-N
C20H16BrClN2O
SCHEMBL745376
orb1704546
SCHEMBL29432589
CHEBI:91468
HMS3229J13
HMS3266H20
HMS3413F20
HMS3677F20
BDBM50136885
EX-A14262
MFCD11100188
AKOS024457329
NCGC00346804-01
NCGC00346804-02
MS-32956
DB-130949
HY-108647
CS-0029384
T22765
BRD-K42452249-001-01-7
BRD-K42452249-001-02-5
BRD-K42452249-001-03-3

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