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NVP-AEW541
SynDRA canonical compound SYN0086708 — structure-anchored drug synonym record
| Primary target(s) | IGF1R |
|---|
| Mechanism of action | IGF-1 inhibitor |
|---|
All known targets
Mechanisms of action (all sources)
- IGF-1 inhibitor
- IGF1R INHIBITOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- NOX4
- NOX3
- CYBB
- ADRA2A
- GAA
- SNCA
- RACGAP1
- PIN1
- OPRK1
- MAPT
- HTR2B
- GBA1
- EHMT2
- ADRA2B
- DRD3
- CHRM2
- CHRM1
- ATAD5
- AR
- APP
- APOBEC3F
- ALOX15
- ADRA2C
- TDP1
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- 5HT2B
- CP2C9
- CY24B
- DRD2
- IF4H
- LYAG
- PABP1
- RGAP1
- SYUA
Cross-references
Synonyms
- CCG-269117
- EBC-520312
- HY-50866B
- AEW-541
- HY-50866
- SCHEMBL1441421
- NVP AEW541
- AEW541
- DTXCID70417929
- BRD-K24696047-001-02-3
- T69682
- AEW-541 free base
- NVP-AEW 541
- AKOS032947252
- AVP-AEW541
- NCGC00346461-03
- NSC-767006
- T6080
- CS-0181258
- MFCD22741515
- SCHEMBL29561027
- HMS3654O07
- BDBM50157879
- AC-32800
- N8561
- orb1301091
- NVP-AEW541 (dihydrochloride)
- NVP-AEW541-A
- VSD26163
- NSC767006
- AKOS027338692
- [7-[cis-3-[(Azetidin-1-yl)methyl]cyclobutyl]-5-(3-benzyloxyphenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]amine
- NCGC00346461-05
- SW219740-1
- PB19343
- NSC-799326
- NCGC00386199-02
- NVP-AEW541 (hydrochloride)
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