simvastatin

SynDRA canonical compound SYN0086701 — structure-anchored drug synonym record

Primary target(s)	HMGCR
Mechanism of action	HMGCR inhibitor

All known targets

HMGCR

Mechanisms of action (all sources)

HMGCR INHIBITOR

Bioactivity evidence (ChEMBL activities table — not curator-asserted)

CYP2C19
CYP2C9
EGFR
MAP2K1
NR1I2
PTK2
STK4
CYP1A2
CYP2D6
HDAC6

Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)

CP2C9
CP2D6
CP3A7
HLAB
IFNB1
KSYK
NSD2
NTM1A
NTMT1
SYK
TP53

Cross-references

PubChem CID: 73707467
ChEBI: 94560
LINCS BRD: BRD-K28026280

Synonyms

CHEBI:94560
BRD-K28026280-001-01-7
[(1S,3R,7S,8R,8aS)-8-[2-[(2R,4R)-4-hydroxy-6-oxooxan-2-yl]ethyl]-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl] 2,2-dimethylbutanoate

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