veliparib

SynDRA canonical compound SYN0086667 — structure-anchored drug synonym record

Primary target(s)	PARP1
Mechanism of action	PARP inhibitor

All known targets

PARP1
PARP2

Mechanisms of action (all sources)

PARP inhibitor

Bioactivity evidence (ChEMBL activities table — not curator-asserted)

ALDH1A1
MBNL1
USP1
THRB
TDP1
SNCA
SMN1
RGS4
RECQL
POLK
POLI
PMP22
NPSR1
MPHOSPH8
MAPT
APEX1
LMNA
KMT2A
KCNH2
IDH1
HPGD
GMNN
GAA
FEN1
EHMT2
ATXN2
ARSA
APP
VDR

Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)

ADCY9
GLSK
KSYK
NSD2
PHGDH
SYK
THB

Cross-references

PubChem CID: 11842604
ChEMBL: CHEMBL497608
PDB: 3GN
LINCS BRD: BRD-K12737986

Synonyms

PARP-2/1-IN-2
(R)-Modafinil-d10 Carboxylate Methyl Ester
3GN
MFCD26954827
benzimidazole carboxamide, 4a
SCHEMBL422319
orb1744617
SCHEMBL1804772
SCHEMBL30418660
BDBM27136
HMS3654G03
HMS3743A13
DA-76606
HY-105253
CS-0025512
SW219820-1
F13345
BRD-K12737986-001-01-4
2-[(2S)-2-methylpyrrolidin-2-yl]-1H-benzimidazole-7-carboxamide

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