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endo-IWR-1
SynDRA canonical compound SYN0086663 — structure-anchored drug synonym record
| Clinical phase | Preclinical |
|---|
| Primary target(s) | TNKS |
|---|
| Mechanism of action | PARP inhibitor |
|---|
All known targets
Mechanisms of action (all sources)
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- TNKS2
- TNKS
- CYP1A2
- PARP15
- ACHE
- LMNA
- MMP9
- MMP1
- MC5R
- MC4R
- MC3R
- MAPK3
- MAPK14
- MAPK1
- MAOA
- KDM4E
- LCK
- NPY1R
- KCNH2
- KCNA3
- HTR6
- HTR2C
- HTR2B
- HTR2A
- HSD17B10
- HRH2
- HRH1
- HMGCR
- NFE2L2
- NR3C1
- NPY2R
- PTPRC
- TDP1
- TBXAS1
- TARDBP
- TACR2
- TACR1
- SNCA
- SLC6A4
- SLC6A3
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
Cross-references
Synonyms
- IWR-1-endo
- CHEBI:62882
- RefChem:1087883
- IWR-1
- endo-IWR 1
- MFCD18086875
- C25H19N3O3
- endo-IWR 1;IWR-1-endo
- 4tkf
- IRW1
- SCHEMBL15315470
- SCHEMBL29351492
- SCHEMBL29915432
- SCHEMBL30661658
- EX-A642
- BDBM50007583
- NSC756646
- AKOS027326646
- CCG-208104
- FI24746
- NSC-756646
- IWR-1, >=98% (HPLC)
- AC-35923
- HY-12238
- I9068
- C71420
- F811916
- BRD-K61314889-001-01-0
- BRD-K61314889-001-04-4
- BRD-K61314889-001-05-1
- HMS3677N22
- SCHEMBL29350238
- AKOS024457668
- HMS3413N22
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