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GANT-58

SynDRA canonical compound SYN0086638 — structure-anchored drug synonym record

All known targets

• GLI1
• DHH
• IHH

Mechanisms of action (all sources)

• GLI1 ANTAGONIST

Bioactivity evidence (ChEMBL activities table — not curator-asserted)

• ALDH1A1
• ALOX15B
• CTSB
• CTSL
• CYP1A2
• CYP2C19
• CYP2C9
• CYP2D6
• CYP3A4
• HDAC6
• NPC1

Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)

• CP2D6
• KSYK
• NSD2
• SYK

Cross-references

• PubChem CID: 253078
• ChEMBL: CHEMBL472994
• ChEBI: 94284
• LINCS BRD: BRD-K64451768

Synonyms

• 4,4',4'',4'''-(Thiene-2,3,4,5-tetrayl)tetrapyridine
• RefChem:1069218
• DTXCID80242582
• GANT58
• 2,3,4,5-tetra(4-pyridyl)thiophene
• 4,4',4'',4'''-(Thiophene-2,3,4,5-tetrayl)tetrapyridine
• 2,3,4,5-tetra-(4-pyridyl)-thiophene
• 4-(2,4,5-tripyridin-4-ylthiophen-3-yl)pyridine
• NSC75503
• MFCD01103196
• NSC-75503
• MLS000736819
• C24H16N4S
• 4-(2,4,5-tri(4-pyridinyl)-3-thienyl)pyridine
• 4-[2,4,5-tris(4-pyridyl)-3-thienyl]pyridine
• NCIStruc1_001570
• NCIStruc2_001490
• orb1308281
• GANT58,NSC75503
• SCHEMBL15150098
• CHEBI:94284
• EX-A12242N
• HMS2807J23
• NCI75503
• BDBM50249102
• CCG-36926
• HB3313
• NCGC00013822
• AKOS024363180
• CS-0507
• GANT58, >=98% (HPLC)
• NCGC00013822-02
• NCGC00013822-03
• NCGC00013822-10
• NCGC00096932-01
• AC-36921
• AS-78051
• HY-13282
• NCI60_041654