afatinib

SynDRA canonical compound SYN0086630 — structure-anchored drug synonym record

Primary target(s)	ERBB4
Mechanism of action	EGFR inhibitor

All known targets

EGFR
ERBB2
ERBB4

Mechanisms of action (all sources)

EGFR INHIBITOR

Bioactivity evidence (ChEMBL activities table — not curator-asserted)

ERBB2
HDAC6
MAPT
POLK
VDR

Cross-references

PubChem CID: 57519523
ChEBI: CHEBI:94698
LINCS BRD: BRD-K66175015

Synonyms

SCHEMBL185621
orb1305744
SCHEMBL29511682
NCGC00185000-02
NCGC00185000-03
F980217
N-[4-(3-chloro-4-fluoroanilino)-7-[[(3S)-3-oxolanyl]oxy]-6-quinazolinyl]-4-(dimethylamino)-2-butenamide

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