BIX-02189

SynDRA canonical compound SYN0086605 — structure-anchored drug synonym record

Clinical phase	Preclinical
Primary target(s)	MAP2K5
Mechanism of action	MEK inhibitor

All known targets

MAP2K5
MAPK7
TGFBR1

Mechanisms of action (all sources)

MEK inhibitor
MAPK7 INHIBITOR
MAP2K5 INHIBITOR
TGFBR1 INHIBITOR

Bioactivity evidence (ChEMBL activities table — not curator-asserted)

HDAC6
HSPA5
POLK
TDP1

Cross-references

PubChem CID: 73265217
ChEMBL: CHEMBL3182395
ChEBI: CHEBI:91423
LINCS BRD: BRD-K73368362

Synonyms

3-[[3-[(dimethylamino)methyl]anilino]-phenylmethylidene]-N,N-dimethyl-2-oxo-1H-indole-6-carboxamide

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