← SynDRA

tofacitinib

SynDRA canonical compound SYN0086594 — structure-anchored drug synonym record

All known targets

• JAK1
• JAK2
• JAK3

Mechanisms of action (all sources)

• JAK inhibitor

Bioactivity evidence (ChEMBL activities table — not curator-asserted)

• HDAC6
• MAPK10
• MAPK9

Cross-references

• PubChem CID: 25180101
• ChEMBL: CHEMBL457871
• ChEBI: 176764
• LINCS BRD: BRD-K36280065

Synonyms

• B64WR5WNB7
• Epitofacitinib, (3R,4S)-
• RefChem:1084153
• (3R,4S)-Tofacitinib
• (3R,4S)-(+)-Tofacitinib isomer
• Tofacitinib Impurity 1
• MFCD23160057
• Tofacitinib Impurity O
• TRANS-TOFACITINIB
• UNII-B64WR5WNB7
• SCHEMBL28416782
• SCHEMBL30925309
• CHEBI:176764
• STB57846
• BDBM50273894
• HY-40354D
• AKOS027383991
• CS-1109
• AS-74809
• DB-251674
• SW220133-2
• D86134
• F85594
• F863222
• BRD-K36280065-001-01-1
• BRD-K36280065-048-01-2
• (3R,4S)-4-Methyl-3-(methyl-7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)-beta-oxo-1-piperidinepropanenitrile