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CHIR-124
SynDRA canonical compound SYN0086567 — structure-anchored drug synonym record
| Clinical phase | Preclinical |
|---|
| Primary target(s) | CHEK1 |
|---|
| Mechanism of action | CHK inhibitor |
|---|
All known targets
Mechanisms of action (all sources)
- CHK inhibitor
- CHEK1 INHIBITOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- AURKA
- AAK1
- NEK3
- PEBP1
- PDXK
- PDGFRB
- PASK
- PAK6
- PAK4
- PAK2
- PAICS
- OPA1
- OLA1
- NUAK2
- NTRK1
- NTHL1
- NQO2
- NLK
- NEK9
- PFKP
- PGRMC1
- PHKG2
- PRKAA1
- PRKCA
- PRKAR2A
- PRKAG2
- PRKAG1
- PRKACG
- PRKACB
- PRKACA
- PLK4
- PIM1
- PLK1
- PKN3
- PKN2
- PKN1
- PKMYT1
- PIP4K2C
- PIP4K2A
- NEK7
Cross-references
Synonyms
- 5K64W8EU3E
- RefChem:125215
- CHIR124
- C23H22ClN5O
- UNII-5K64W8EU3E
- MLS006011027
- GTPL9365
- orb1300845
- SCHEMBL3383518
- SCHEMBL29387680
- BDBM50185219
- EX-A14120
- MFCD31656992
- s2683
- AKOS027288999
- CCG-268885
- compound 11 [PMID: 6603354]
- CS-0482
- SDCCGSBI-0654450.P001
- NCGC00346626-01
- NCGC00346626-02
- NCGC00346626-04
- NCGC00346626-06
- AC-32840
- HY-13263
- MS-27360
- SMR004702822
- DB-027176
- NS00071949
- SW219499-1
- BRD-K02241333-001-02-7
- 4-[(3S)-1-AZABICYCLO[2.2.2]OCT-3-YLAMINO]-3-(1H-BENZIMIDAZOL-2-YL)-6-CHLOROQUINOLIN-2(1H)-ONE
- SCHEMBL31207550
- SCHEMBL29379375
- SCHEMBL3384695
- BDBM50414084
Look up CHIR-124 in the interactive SynDRA portal →