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PP-1
SynDRA canonical compound SYN0079293 — structure-anchored drug synonym record
| Clinical phase | Preclinical |
|---|
| Primary target(s) | HCK | RET | SRC |
|---|
| Mechanism of action | SRC inhibitor |
|---|
All known targets
- CSK
- EGFR
- FYN
- LCK
- MAPK14
- WNK1
Mechanisms of action (all sources)
- CSK INHIBITOR
- EGFR INHIBITOR
- FYN INHIBITOR
- LCK INHIBITOR
- MAPK14 INHIBITOR
- WNK1 INHIBITOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ABL1
- EGFR
- EPHB4
- HCK
- KDR
- MTOR
- PIK3CA
- PIK3CB
- PIK3CD
- PIK3CG
- PRKDC
- SRC
- PI4KB
Cross-references
Synonyms
- 1-Ter-Butyl-3-P-Tolyl-1h-Pyrazolo[3,4-D]Pyrimidin-4-Ylamine
- 1-Ter-Butyl-3-P-Tolyl-1h-Pyrazolo(3,4-D)Pyrimidin-4-Ylamine
- RefChem:436568
- PP1
- PYRAZOLOPYRIMIDINE 1
- MFCD01076570
- SA2ND7EHY4
- PP-1 (enzyme inhibitor)
- AGL 1872
- EI-275
- 1-tert-butyl-3-p-tolyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine
- 1-tert-butyl-3-(p-tolyl)pyrazolo[3,4-d]pyrimidin-4-amine
- 4fev
- ZVPDNRVYHLRXLX-UHFFFAOYSA-N
- Kinome_2004
- pp1?
- BiomolKI_000024
- UNII-SA2ND7EHY4
- BiomolKI2_000032
- cid_1400
- CBiol_001915
- Oprea1_734810
- BSPBio_001034
- KBioGR_000374
- KBioSS_000374
- ksc-8-189
- MLS000326642
- SCHEMBL407934
- BMK1-C12
- GTPL8836
- orb1300990
- SCHEMBL29432587
- BCBcMAP01_000234
- BDBM25116
- KBio2_000374
- KBio2_002942
- KBio2_005510
- KBio3_000727
- KBio3_000728
Look up PP-1 in the interactive SynDRA portal →