CGH-2466

SynDRA canonical compound SYN0078838 — structure-anchored drug synonym record

Clinical phase	Preclinical
Primary target(s)	ADORA1 \| ADORA2B \| ADORA3
Mechanism of action	adenosine receptor antagonist

Bioactivity evidence (ChEMBL activities table — not curator-asserted)

CYP3A4
TLK1
BAZ2B
CBX1
GMNN
IKBKB
JAK2
KDM4A
PRKCB
PRKCQ
RAF1
SMAD3
SMPD1
TDP1
UBE2N

Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)

BARD1
BRCA1
CP2C9
CP3A7
GNA15
IL1B
KSYK
MDM2
MDM4
NSD2
SYK
TAAR1

Cross-references

PubChem CID: 5282339
ChEMBL: CHEMBL1624302
ChEBI: 34599
KEGG: C14128
LINCS BRD: BRD-K82028950

Synonyms

CGH 2466
4-(3,4-Dichlorophenyl)-5-(4-pyridinyl)-2-thiazolamine
4-(3,4-Dichlorophenyl)-5-(pyridin-4-yl)thiazol-2-amine
4-(3,4-dichlorophenyl)-5-pyridin-4-yl-1,3-thiazol-2-amine
C14128
AC1NQZWM
CTK8E9516
LS-192831
SCHEMBL1223368
SCHEMBL29394682
CHEBI:34599
4-(3,4-DICHLOROPHENYL)-5-(PYRIDIN-4-YL)-1,3-THIAZOL-2-AMINE
NCGC00092379-02
DB-395493
BRD-K82028950-300-01-1
BRD-K82028950-300-02-9
4-(3,4-dichlorophenyl)-5-(4-pyridyl)thiazol-2-amine
EX-A14428
CGH2466
Cgh 2466 dihydrochloride
MS-33282
AKOS024457061
CGH2466 (dihydrochloride)
HY-103167
NCGC00092379-01
SCHEMBL16102298
CGH2466 dihydrochloride

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