← SynDRA

PRT-062607

SynDRA canonical compound SYN0062933 — structure-anchored drug synonym record

All known targets

• SYK
• FGR
• MAP3K9

Mechanisms of action (all sources)

• SYK INHIBITOR

Bioactivity evidence (ChEMBL activities table — not curator-asserted)

• APP
• HDAC6
• HTT

Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)

• CP1A2

Cross-references

• PubChem CID: 44462758
• ChEMBL: CHEMBL2177736
• PDB: 3YT
• TTD: D0R9IU
• LINCS BRD: BRD-K53734668

Synonyms

• (REL)-P505-15
• (REL)-PRT062607
• BIIB-057
• BIIB057
• P 505-15
• P505-15
• PRT-2607
• PRT062607
• P-14276
• P-505-15
• Syk tyrosine kinase inhibitors (oral, cancers/inflammatory diseases/thrombosis), Portola
• PRT 062607
• CHEMBL2177736
• K9C42672RH
• 2-[[(1R,2S)-2-aminocyclohexyl]amino]-4-[3-(triazol-2-yl)anilino]pyrimidine-5-carboxamide
• 2-[[(1R,2S)-2-aminocyclohexyl]amino]-4-[[3-(2H-1,2,3-triazol-2-yl)phenyl]amino]-5-pyrimidinecarboxamide
• 4-((3-(2H-1,2,3-Triazol-2-yl)phenyl)amino)-2-(((1R,2S)-2-aminocyclohexyl)amino)pyrimidine-5-carboxamide
• 4-(3-(2H-1,2,3-Triazol-2-yl)phenylamino)-2-((1R,2S)-2-aminocyclohexylamino)pyrimidine-5-carboxamide
• 5-Pyrimidinecarboxamide, 2-(((1R,2S)-2-aminocyclohexyl)amino)-4-((3-(2H-1,2,3-triazol-2-yl)phenyl)amino)-
• 2-{[(1r,2s)-2-Aminocyclohexyl]amino}-4-{[3-(2h-1,2,3-Triazol-2-Yl)phenyl]amino}pyrimidine-5-Carboxamide
• SCHEMBL899872
• UNII-K9C42672RH
• GTPL8070
• AMY9038
• EX-A1592
• BDBM50400047
• NSC776786
• ZINC95572830
• CS-3535
• NSC-776786
• NCGC00351606-09
• HY-15322
• E98978
• BRD-K53734668-003-04-6
• Q27088231
• P505-15, PRT062607,PRT-2607, BIIB-057
• 4-(3-(2H-1,2,3-TRIAZO-2-YL)PHENYLAMINO)-2-((1R,2S)-2-AMINOCYCLOHEXYLAMINO) PYRIMIDINE-5-CARBOXAMIDE
• 5-Pyrimidinecarboxamide, 2-[[(1R,2S)-2-aminocyclohexyl]amino]-4-[[3-(2H-1,2,3-triazol-2-yl)phenyl]amino]-, rel-
• PRT062607 Hydrochloride