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JW-55
SynDRA canonical compound SYN0062932 — structure-anchored drug synonym record
| Clinical phase | Preclinical |
|---|
| Primary target(s) | TNKS | TNKS2 |
|---|
| Mechanism of action | tankyrase inhibitor |
|---|
All known targets
Mechanisms of action (all sources)
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- JAK2
- KCNH2
- YES1
- SRC
- PRKCA
- PAK5
- LYN
- LCK
- ZAP70
- FLT3
- GSK3B
- HDAC6
- AURKA
- FGFR2
- CYP3A4
- MAPK1
- CSNK1D
- CDK2
- BRPF1
- TRIM24
- BRD4
- ABL1
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- IFNB1
- IFNG
- KSYK
- M3K9
- NSD2
- TP53
Cross-references
Synonyms
- C25H26N2O5
- JW55
- N-[4-({[4-(4-METHOXYPHENYL)OXAN-4-YL]METHYL}CARBAMOYL)PHENYL]FURAN-2-CARBOXAMIDE
- JW 55
- RefChem:350326
- DTXCID10338962
- jw55
- MFCD03863265
- JW55 Inhibitor
- orb1307402
- SCHEMBL1896657
- CHEBI:95068
- EX-A274
- GLXC-02754
- HMS1591J12
- HMS3426G05
- JW55?
- PBB99353
- Tankyrase1/2 Inhibitor IV, JW55
- BDBM50136777
- s6745
- STK774983
- AKOS001733937
- CS-1757
- NCGC00379145-08
- NCGC00379145-12
- AC-35206
- AS-16546
- DA-33454
- HY-13968
- J8800
- T1807
- AL-281/42013130
- F869540
- SR-01000269072
- SR-01000269072-1
- A95
- N-[4-[[[[Tetrahydro-4-(4-methoxyphenyl)-2H-pyran-4-yl]methyl]amino]carbonyl]phenyl]-2-furancarboxamide
- N-[4-[[[4-(4-methoxyphenyl)-4-oxanyl]methylamino]-oxomethyl]phenyl]-2-furancarboxamide
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