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ML-281
SynDRA canonical compound SYN0062930 — structure-anchored drug synonym record
| Clinical phase | Preclinical |
|---|
| Primary target(s) | STK33 |
|---|
| Mechanism of action | serine/threonine kinase inhibitor |
|---|
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ABL1
- NEK2
- PKN2
- PIM3
- PIM2
- PIM1
- PHKG2
- PDPK1
- PBK
- PAK4
- PAK1
- NTRK3
- NTRK2
- NTRK1
- NEK4
- MKNK2
- AKT1
- MINK1
- MET
- MELK
- MATK
- MARK3
- MAPKAPK5
- MAPKAPK3
- MAPKAPK2
- MAPK9
- MAPK8
- MAPK13
- MAPK12
- MAPK1
- PLK1
- PLK3
- PLK4
- PRKAA1
- TYK2
- TSSK2
- TSSK1B
- TAOK1
- STK3
- STK17A
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- ALOX12
- KSYK
- NSD2
- NR1I3
- MK01
- M4K4
- M4K2
- LOX12
- KPCD3
- CP2C9
- KPCD2
- KCC2G
- IFNB1
- HLAB
- DYR1A
- CP3A7
- TP53
Cross-references
Synonyms
- ML281
- MFCD25976601
- bg-stk33-59
- MLS003876599
- orb1304214
- SCHEMBL28712145
- SCHEMBL30239895
- SCHEMBL31580984
- BRD8942
- EX-A996
- CHEBI:125325
- BRD-8942
- EGC43762
- BDBM50400664
- ML281?
- AKOS024458394
- CS-5682
- NCGC00379225-02
- AC-30951
- BS-15376
- DA-55534
- HY-13495
- SMR002533153
- F861829
- BRD-K48188942-001-01-1
- N-[2-(3-oxo-4H-quinoxalin-2-yl)-4-propan-2-ylphenyl]-2-thiophenecarboxamide
Look up ML-281 in the interactive SynDRA portal →