trap-101

SynDRA canonical compound SYN0062878 — structure-anchored drug synonym record

Clinical phase	Preclinical
Primary target(s)	OPRL1
Mechanism of action	Opioid receptor antagonist

All known targets

OPRL1

Mechanisms of action (all sources)

NOP receptor antagonist
Opioid receptor antagonist
nociceptin/orphanin FQ receptor antagonist

Bioactivity evidence (ChEMBL activities table — not curator-asserted)

ALOX12
CYP1A2
CYP2C19
CYP2C9
CYP2D6
CYP3A4
RGS4
TDP1
TP53

Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)

GCR
MYC

Cross-references

PubChem CID: 11494970
ChEMBL: CHEMBL3182208
ChEBI: 93227
LINCS BRD: BRD-K69837166

Synonyms

RefChem:907140
Trap101
SCHEMBL29766974
CHEBI:93227
GTPL10499
NCGC00167753-01
BRD-K69837166-003-01-2
BRD-K69837166-003-02-0
1-[1-(cyclooctylmethyl)-5-(hydroxymethyl)-3,6-dihydro-2H-pyridin-4-yl]-3-ethyl-2-benzimidazolone

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