← SynDRA
DMBI
SynDRA canonical compound SYN0062867 — structure-anchored drug synonym record
| Primary target(s) | PDGFRB |
|---|
| Mechanism of action | VEGFR inhibitor |
|---|
All known targets
Mechanisms of action (all sources)
- PDGFR inhibitor
- VEGFR inhibitor
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ALDH1A1
- ATXN2
- UBE2N
- TDP1
- SMAD3
- RCE1
- RAPGEF3
- RAD52
- POLI
- PKM
- NPSR1
- MAPT
- LMNA
- KMT2A
- KDM4E
- IDH1
- HDAC6
- GMNN
- GLP1R
- GBA1
- EHMT2
- CGA
- BAZ2B
- VCP
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- 5HT5A
- OPRM
- NCF1
- NPBW1
- NSD2
- NTM1A
- NTMT1
- OPRD
- OXYR
- MDM2
- PE2R2
- PPP1CA
- RXFP1
- SYK
- TERA
- TR10B
- MDM4
- MCL1
- ACM4
- DRD1
- ACM5
- ADRB2
- APAF
- APLNR
- BARD1
- BRCA1
- GPR55
- M4K2
- HCRTR1
- IDHC
- IFNB1
- IFNG
- IL1B
- KSYK
- V1AR
Cross-references
Synonyms
- NSC-86429
- SU-4312
- MFCD00118147
- (3E)-3-[[4-(dimethylamino)phenyl]methylidene]-1H-indol-2-one
- 3-[4-(Dimethylamino)benzylidene]indolin-2-one
- QTW8MQ534B
- 3-(4-(dimethylamino)benzylidene)indolin-2-one
- Tocris-1459
- trans-SU4312
- trans-SU 4312
- Lopac-S-8567
- GTPL5958
- SCHEMBL13394695
- HMS3229C19
- BDBM50111603
- EBC-00639
- EBC-55059
- HSCI1_000057
- AKOS001034409
- CCG-206747
- NCGC00015974-01
- NCGC00025170-01
- SU 4312, >=98% (HPLC)
- EN300-1700023
- EN300-21584684
- BRD-K60487568-001-01-3
- BRD-K96084870-001-01-9
- Z44305798
- (3E)-3-[[4-(dimethylamino)phenyl]methylene]indolin-2-one
- 3-(4-Dimethylamino-benzylidene)-1,3-dihydro-indol-2-one
- 3-(4-dimethylaminobenzylidenyl)-2-indolinone
Look up DMBI in the interactive SynDRA portal →