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BRD-K93725829
SynDRA canonical compound SYN0062537 — structure-anchored drug synonym record
| Clinical phase | Preclinical |
|---|
| Primary target(s) | MAPK1 |
|---|
| Mechanism of action | MAP kinase inhibitor |
|---|
All known targets
Mechanisms of action (all sources)
- AURKA INHIBITOR
- CDK2 INHIBITOR
- MAPK1 INHIBITOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- CYP2C19
- CYP2C9
- CYP2D6
- CYP3A4
- HDAC6
- KAT2A
- KDM4E
- RGS4
- USP1
Cross-references
Synonyms
- ERK-inhibitor-11E
- RefChem:912040
- VX-11e
- VTX-11e
- VX11E
- NCGC00242487
- C24H20Cl2FN5O2
- Vertex 11e
- pyrimidylpyrrole, 11e
- ERK11e
- ERK-11e
- GTPL9375
- orb1304470
- SCHEMBL15859235
- SCHEMBL29351720
- VX-11e(TCS ERK 11e)
- BDBM35657
- CHEBI:95049
- GLXC-05348
- VX-11e(TCS ERK 11e)?
- EX-A1570
- s7709
- AKOS024458172
- CCG-269689
- CS-0995
- NCGC00242487-01
- NCGC00242487-02
- NCGC00242487-06
- NCGC00242487-09
- AC-29012
- AS-16952
- HY-14178
- V9201
- C77026
- F863781
- BRD-K93725829-001-01-2
- BRD-K93725829-001-03-8
- 4-[2-(2-chloro-4-fluoroanilino)-5-methyl-4-pyrimidinyl]-N-[(1S)-1-(3-chlorophenyl)-2-hydroxyethyl]-1H-pyrrole-2-carboxamide
- 4-[2-[(2-Chloro-4-fluorophenyl)amino]-5-methyl-4-pyrimidinyl]-N-[(1S)-1-(3-chlorophenyl)-2-hydroxyethyl]-1H-pyrrole-2-carboxamide
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