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XE-991
SynDRA canonical compound SYN0059241 — structure-anchored drug synonym record
| Clinical phase | Preclinical |
|---|
| Primary target(s) | KCNQ3 |
|---|
| Mechanism of action | Potassium channel blocker |
|---|
All known targets
- KCNQ1
- KCNQ2
- KCNQ3
- KCNQ4
- KCNQ5
Mechanisms of action (all sources)
- Potassium channel blocker
- KCNQ1 MODULATOR
- KCNQ2 MODULATOR
- KCNQ4 MODULATOR
- KCNQ5 MODULATOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- ABC3G
- ABL1
- RIN1
- PSIP1
- PPARG
- PEBB
- NR0B1
- NCOR2
- MLLT3
- MITF
- MEN1
- MBNL1
- KMT2A
- IL1B
- HTT
- DNMT1
- BAZ2B
- RUNX1
Cross-references
Synonyms
- XE 991
- DR 960418
- XE 991, anthracenone
- XE991 cpd
- RefChem:436919
- XE991
- LS-190926
- 9(10H)-Anthracenone, 10,10-bis(4-pyridinylmethyl)-
- Tocris-2000
- CHEBI:35046
- NCGC00025339-01
- GTPL2596
- orb1944530
- SCHEMBL2761225
- SCHEMBL29384236
- KHJFBUUFMUBONL-UHFFFAOYSA-N
- BDBM50529215
- MFCD05662331
- MFCD09055426
- HY-108577A
- XE-991, >=98% (HPLC)
- CS-0084011
- G89970
- T78570
- BRD-K42748308-300-01-2
- BRD-K42748308-300-02-0
- XEA95513
- DA-79005
- orb1307601
- C26H22Cl2N2O
- SR-01000597960-1
- XE991Dihydrochloride
- XE 991 dihydrochloride
- XE991 Dihydrochloride
- AKOS024456903
- HY-108577
- s2967
- XE 991 2HCl
- SCHEMBL27203219
Look up XE-991 in the interactive SynDRA portal →