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H-89
SynDRA canonical compound SYN0054896 — structure-anchored drug synonym record
| Primary target(s) | PRKACA |
|---|
| Mechanism of action | PKA inhibitor |
|---|
All known targets
Mechanisms of action (all sources)
- PKA inhibitor
- PRKACA INHIBITOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ABL1
- CYP2C19
- MAPK1
- KCNH2
- HDAC6
- GSK3B
- FGFR3
- CYP3A4
- CYP2J2
- CYP2C9
- CYP2C18
- AURKA
- CYP2B6
- CYP2A6
- CYP1A2
- CSNK1D
- CDK2
- CA2
- BRPF1
- BRD4
- TRIM24
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- AHR
- CP1A2
- CP2C9
- CP2CJ
- CP3A4
- GLI3
- NF2L2
Cross-references
Synonyms
- N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide
- MFCD00214119
- Kinome_2783
- CBiol_002015
- KBioGR_000447
- KBioSS_000447
- SCHEMBL123496
- orb1709506
- SCHEMBL29967929
- KBio2_000447
- KBio2_003015
- KBio2_005583
- KBio3_000833
- KBio3_000834
- Bio1_000301
- Bio1_000790
- Bio1_001279
- Bio2_000384
- Bio2_000864
- HMS3673M11
- HMS3745E05
- SB19596
- NCGC00162073-05
- n-[2-(p-bromocinnamylamino)ethyl]-5-isoquinolinesulphonamide
Look up H-89 in the interactive SynDRA portal →