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AC710
SynDRA canonical compound SYN0049825 — structure-anchored drug synonym record
| Clinical phase | Preclinical |
|---|
| Primary target(s) | CSF1R | FLT3 | KIT | PDGFRA | PDGFRB |
|---|
| Mechanism of action | PDGFR tyrosine kinase receptor inhibitor |
|---|
All known targets
- CSF1R
- FLT3
- KIT
- PDGFRA
- PDGFRB
- CSF3R
Mechanisms of action (all sources)
- CSF1R INHIBITOR
- FLT3 INHIBITOR
- KIT INHIBITOR
- PDGFRA INHIBITOR
- PDGFRB INHIBITOR
- PDGFR tyrosine kinase receptor inhibitor
- CSF3R INHIBITOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- KDR
- SRPK1
- SRPK2
- SRPK3
- CLK1
- CLK2
- CLK3
- CLK4
- DYRK1A
- DYRK1B
- DYRK2
- DYRK3
- SAMHD1
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- CP2C9
- CP2D6
- CP3A7
- KSYK
- SYK
Cross-references
Synonyms
- AC-710
- CPD 22B
- CSF1R inhibitor (cancer), Ambit Biosciences
- CSF1R inhibitor (cancer/autoimmune/inflammatory disease), Ambit Biosciences
- AC 710
- RefChem:108645
- MFCD25976599
- GTPL8095
- orb1296109
- SCHEMBL1698753
- EX-A555
- GLXC-06199
- AC710?
- BDBM50400602
- NSC787038
- AKOS025147321
- CS-3415
- NSC-787038
- SB19144
- NCGC00387454-02
- AC-35877
- AS-82371
- DA-45824
- HY-13493
- AC710 Mesylate
- SCHEMBL29766467
- SCHEMBL1698589
- orb1710499
- CS-3416
- BEC52205
- T10228
- AC-710 Mesylate
- AC710 (Mesylate)
- AKOS030526435
- HY-13493A
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