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sorbinil
SynDRA canonical compound SYN0048807 — structure-anchored drug synonym record
| Primary target(s) | AKR1B1 |
|---|
| Mechanism of action | Aldose reductase inhibitor |
|---|
All known targets
Mechanisms of action (all sources)
- Aldose reductase inhibitor
- AKR1B1 INHIBITOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- DRD2
- ATXN2
- MAPK1
- TDP1
- TARDBP
- TAAR1
- SMN1
- RGS4
- POLI
- POLH
- POLB
- PMP22
- OPRM1
- MTOR
- MPHOSPH8
- KDM4E
- BLM
- KDM4A
- KCNH2
- IDH1
- HSPA5
- HDAC6
- GMNN
- GLS
- GLP1R
- GFER
- GALR3
- EHMT2
- DRD4
- VDR
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- ALR
- COMT
- DRD3
- ESRRA
- GAMT
- GLSK
- GNMT
- HNMT
- HS90A
- HS90B
- NNMT
- NTM1A
- NTMT1
- PNMT
Cross-references
- PubChem CID: 5252
- LINCS BRD: BRD-A89164055
Synonyms
- 6-Fluoro-4-chromanone hydantoin
- 6-Fluoro-4-chromanonehydantoin
- MFCD01569247
- 6-fluorochroman-4-one hydantoin
- 6-fluorospiro[chromane-4,5'-imidazolidine]-2',4'-dione
- MLS003171137
- SCHEMBL2108408
- LXANPKRCLVQAOG-UHFFFAOYSA-N
- SBB098563
- AKOS000280385
- AKOS023600463
- FS-1063
- SMR001875045
- DB-055321
- 6-fluoro-4-chromanone hydantoin, AldrichCPR
- F97690
- F003847
- BRD-A89164055-001-03-3
- (RS)-6-fluoro-spiro-[chroman-4,4'-imidazolidine]-2',5'-dione
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