AZD-1480

SynDRA canonical compound SYN0044267 — structure-anchored drug synonym record

Primary target(s)	JAK2
Mechanism of action	JAK inhibitor

All known targets

JAK1
JAK2
JAK3

Mechanisms of action (all sources)

JAK inhibitor
JAK1 INHIBITOR
JAK2 INHIBITOR
JAK3 INHIBITOR

Bioactivity evidence (ChEMBL activities table — not curator-asserted)

ABCB1
ABCC1
KCNH2
RYR2

Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)

CP2D6
CP3A7
KSYK
NSD2
SYK

Cross-references

PubChem CID: 46861588
ChEMBL: CHEMBL2141865
ChEBI: 91406
LINCS BRD: BRD-A29009894

Synonyms

RefChem:913317
SCHEMBL220400
CHEBI:91406
PDOQBOJDRPLBQU-UHFFFAOYSA-N
HMS3295G23
HMS3655D06
AKOS026750646
SB11067
NCGC00389402-02
BRD-A29009894-001-01-2
5-chloro-N2-[1-(5-fluoro-2-pyrimidinyl)ethyl]-N4-(5-methyl-1H-pyrazol-3-yl)pyrimidine-2,4-diamine

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