neratinib

SynDRA canonical compound SYN0043209 — structure-anchored drug synonym record

Primary target(s)	ERBB4
Mechanism of action	EGFR inhibitor

All known targets

EGFR
ERBB2
ERBB4

Mechanisms of action (all sources)

EGFR INHIBITOR
ERBB2 INHIBITOR

Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)

MITF
TFE3

Cross-references

PubChem CID: 53398697
ChEBI: CHEBI:91335
Wikipedia: Neratinib
LINCS BRD: BRD-K85606544

Synonyms

C30H29ClN6O3
Neratinib(HKI-272)
SCHEMBL571763
SCHEMBL29801657
HMS3265C15
HMS3265C16
HMS3265D15
HMS3265D16
JAC51918
SB16595
NCGC00241101-02
DB-335268
N-[4-[3-chloro-4-(2-pyridinylmethoxy)anilino]-3-cyano-7-ethoxy-6-quinolinyl]-4-(dimethylamino)-2-butenamide

Look up neratinib in the interactive SynDRA portal →