clofarabine

SynDRA canonical compound SYN0043175 — structure-anchored drug synonym record

Primary target(s)	RRM2
Mechanism of action	Ribonucleoside reductase inhibitor

All known targets

RRM1
RRM2
POLA1

Mechanisms of action (all sources)

Ribonucleoside reductase inhibitor
RRM1 INHIBITOR
RRM2 INHIBITOR

Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)

IFNG
KSYK
NSD2
SYK

Cross-references

PubChem CID: 354624
ChEMBL: CHEMBL277800
ChEBI: 91901
LINCS BRD: BRD-A82371568

Synonyms

alpha-Clofarabine
Clolar (Genzyme)
SCHEMBL2887297
CHEBI:91901
HMS3269F07
HMS3654D03
HMS5079M17
BDBM50008368
NSC-606869
SB17339
NCGC00167792-01
NCGC00389786-02
LS-13770
Adenosine, 2-chloro-2'-deoxy-2'-fluoro-
AB01273949-01
BRD-A82371568-001-01-5
5-(6-amino-2-chloro-9-purinyl)-4-fluoro-2-(hydroxymethyl)-3-oxolanol

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