dimethyl-fumarate

SynDRA canonical compound SYN0043006 — structure-anchored drug synonym record

Primary target(s)	KEAP1
Mechanism of action	Kelch-like ECH-associated protein ligand

All known targets

KEAP1
NFE2L2

Mechanisms of action (all sources)

NRF2 activator
NFKB pathway inhibitor
Kelch-like ECH-associated protein ligand

Bioactivity evidence (ChEMBL activities table — not curator-asserted)

TDP1
USP1

Cross-references

PubChem CID: 12215
ChEMBL: CHEMBL3181998
LINCS BRD: BRD-K31111078

Synonyms

Dimethyl but-2-enedioate
2-Butenedioic acid, dimethyl ester
Dimethyl 2-butenedioate
bis(methoxycarbonyl)ethene
SCHEMBL41836
SCHEMBL18166836
cis-Propenoic acid dimethyl ester
LDCRTTXIJACKKU-UHFFFAOYSA-N
HMS3656G20
HMS3867L13
YAA05798
AKOS025243814
NCGC00346639-01
SY004957
DB-054169
NS00099751

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