hydrocortisone

SynDRA canonical compound SYN0042629 — structure-anchored drug synonym record

Primary target(s)	NR3C1
Mechanism of action	Glucocorticoid receptor agonist

All known targets

NR3C1
GPR33
NR3C2

Mechanisms of action (all sources)

NR3C1 AGONIST
GPR33 BINDER
NR3C2 AGONIST

Bioactivity evidence (ChEMBL activities table — not curator-asserted)

ERG
NFE2L2
TDP1

Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)

CFTR
PLCG1

Cross-references

PubChem CID: 3640
ChEMBL: CHEMBL1730629
ChEBI: 95202
LINCS BRD: BRD-A73635141

Synonyms

MLS001074333
pregn-4-ene-3,20-dione, 11,17,21-trihydroxy-
Cortisol-9,11,12,12-d4
SCHEMBL12737556
CHEBI:95202
HMS2230P20
HMS3369A04
HMS5079D14
ALBB-025803
STL372840
AKOS005058485
FC00975
SMR000674616
VS-12198
Cortisol-D4 (9,11,12, 12-D4)
EU-0099955
4-Pregnene-11ss,17a,21-triol-3,20-dione
EN300-296082
SR-01000214153
SR-01000214153-1
11,17,21-Trihydroxypregn-4-ene-3,20-dione

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