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methotrexate
SynDRA canonical compound SYN0042566 — structure-anchored drug synonym record
| Primary target(s) | DHFR |
|---|
| Mechanism of action | Dihydrofolate reductase inhibitor |
|---|
All known targets
- DHFR
- HMGB1
- SLC19A1
- SLC46A1
Mechanisms of action (all sources)
- dihydrofolate reductase inhibitor
- HMGB1 INHIBITOR
- SLC46A1 MODULATOR
- SLC19A1 INHIBITOR
- SLC19A1 MODULATOR
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- ABC3G
- ARNT
- CSTA
- CTDS1
- DYR
- IDHC
- MDR1
- NCOA1
- NCOA3
- NR5A2
- PABP1
- TACC3
- TARDBP
- TR10B
Cross-references
Synonyms
- methrotrexate
- DL-Methotrexate
- NSC-117356
- NSC-757113
- Methotrexate, (A+-)-
- RefChem:1089151
- DL-Amethopterin
- (+/-)Amethopterin
- (+)-Amethopterin
- METHOTREXATE(+/-)
- TCMDC-123832
- Amethopterin (R,S)
- Methotrexate, (+/-)-
- Methotrexate;DL-Amethopterin
- MLS002701970
- ( inverted exclamation markA)-Methotrexate
- Methotrexat-Ebewe
- 6-Mtx (DL)
- (+-)-Methotrexate
- SR-05000001673
- EINECS 262-213-7
- TCMDC-125488
- L(+)-Amethopterin hydrate
- rac-methoetrexat
- NSC117356
- s1210
- Prestwick_753
- Folex (Salt/Mix)
- X 133
- 4-Amino-10-methylfolic acid hydrate
- Prestwick0_000373
- Prestwick1_000373
- Prestwick2_000373
- Prestwick3_000135
- Prestwick3_000373
- SCHEMBL3712
- UNII-99ITO15X8S
- D-(-)-Amethopterin hydrate
- BSPBio_000210
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