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axitinib
SynDRA canonical compound SYN0042384 — structure-anchored drug synonym record
| Primary target(s) | KDR |
|---|
| Mechanism of action | VEGFR inhibitor |
|---|
All known targets
Mechanisms of action (all sources)
- PDGFR inhibitor
- VEGFR inhibitor
- KDR INHIBITOR
- PLK4 INHIBITOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- AURKA
- ABL1
- PAK1
- MST1R
- NEK2
- NEK4
- NTRK1
- NTRK2
- NTRK3
- PAK4
- MINK1
- PASK
- PBK
- PDGFRA
- PDGFRB
- PDPK1
- PHKG2
- MKNK2
- MET
- PIM2
- MAPK14
- MAP4K2
- MAP4K4
- MAP4K5
- MAPK1
- MAPK12
- MAPK13
- MAPK8
- MELK
- MAPK9
- MAPKAPK2
- MAPKAPK3
- MAPKAPK5
- MARK2
- MARK3
- PIM1
- PKN2
- MAP2K2
- SRPK1
- RPS6KA3
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- AAPK1
- M4K5
- VGFR2
- VGFR1
- TSSK1
- PGFRB
- PGFRA
- MK14
- M4K4
- CSK21
- M4K2
- M3K20
- KS6B1
- KS6A3
- KCC2G
- KCC2D
- VGFR3
Cross-references
Synonyms
- RefChem:830393
- DTXCID30810477
- C22H18N4OS
- Axitinib?
- Kinome_3641
- SCHEMBL843204
- SCHEMBL29387511
- HMS3244B04
- HMS3244B08
- HMS3244B12
- HMS3654I03
- HMS3674G15
- BVB62389
- AKOS030228495
- SB20061
- NCGC00241108-03
- N-methyl-2-[[3-[2-(2-pyridinyl)ethenyl]-1H-indazol-6-yl]thio]benzamide
Look up axitinib in the interactive SynDRA portal →