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isoconazole
SynDRA canonical compound SYN0041643 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Primary target(s) | CYP17A1 |
|---|
| Mechanism of action | fungal lanosterol demethylase inhibitor |
|---|
| Indication | gram-positive bacterial infections |
|---|
| Disease area | infectious disease |
|---|
All known targets
Mechanisms of action (all sources)
- fungal lanosterol demethylase inhibitor
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ALOX15
- ALOX15B
- CYP1A2
- CYP2C19
- CYP2C9
- CYP2D6
- CYP3A4
- GMNN
- HIF1A
- LMNA
- TDP1
- TSHR
- USP1
- USP2
- VDR
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- CP1A2
- CP2C9
- CP2CJ
- CP2D6
- CP3A4
Drug classes
- Anti-Infective Agents
- Antifungal Agents
ATC classes
- ANTIFUNGALS FOR TOPICAL USE
- ANTIINFECTIVES AND ANTISEPTICS, EXCL. COMBINATIONS WITH CORTICOSTEROIDS
Cross-references
Synonyms
- isoconazole nitrate
- Isoconazole, (R)-
- (R)-isoconazole
- UNII-14J833G08Q
- NCGC00016800-01
- CAS-27523-40-6
- Miconazole Nitrate Impurity 19
- SCHEMBL24534353
- CHEBI:83666
- (R)-isoconazole nitrate
- CHEBI:83669
- ISOCONAZOLE NITRATE, (R)-
- Z375MCM79E
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